ABSTRACT
In present manuscript describes synthesis of silver nanoparticles using turmeric leaves extract, traditional turmeric is a common spice that comes from the root of Curcuma longa, chemical called curcumin. Turmeric has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. People commonly use turmeric for osteoarthritis, hay fever, depression, high cholesterol, liver disease, itching. There is also no good evidence to support using turmeric for COVID-19. Synthesis of silver nanoparticles AgNO powder was dissolved in distilled water to prepare 10 mM AgNO stock 3 3 solution from which different composition prepared. The AgNO solutions were mixed with urmeric plants 3 t leaves extract in equal proportion in flask. The flask was wrapped with an aluminum foil and was then heated in a water bath at 50-60 C for 2 hours. The synthesis of nanoparticles, which was confirmed by UVSpectra and TEM. UV-Vis spectra and visual observation showed that the color of the fresh leaf extractsof Vinca rosea turned into brownish yellow, respectively, after treatment with silver. In addition, TEM analysis confirmed that AgNO solutions for all concentrations produced ilver nanoparticles and their average size 3 s was less than 20 nm. Turmeric plants extract of fresh leaves can be used as bioreducing agents, drug resistant strains, toxic nature towards microbial agents, play an important role in nanoscience and nanotechnology, particularly in nanomedicine and potential applications in cancer diagnosis and therapy.
ABSTRACT
Background: The rapid global spread of the COVID-19 pandemic urged scientists to search for effective and safe anti-coronavirus drugs from natural resources. Through centuries, traditional medicinal plants have been providing cure for diseases and general health care worldwide. Objective(s): The main aim of this review was to explore and summarize the research works on the different plants used traditionally in Sudan to treat signs and symptoms of COVID-19 and respiratory diseases, characterizing their antiviral activities and exploring the different phytochemicals present in these plants. Method(s): The current review was carried out in line with the recommendations of the PRISMA 2020 statement. Information on plants traditionally used in Sudan to treat the signs and symptoms of COVID-19 and respiratory diseases was obtained from traditional medicine books and published articles, as well as the daily practice by ordinary people. Result(s): This article illustrated the use of 27 plant species belonging to 15 families in Sudanese traditional medicine to treat signs and symptoms of COVID-19 and respiratory diseases. Legumi-nosae/Fabaceae was found to be the most represented family (7 species), followed by Combretaceae (3 species) and Capparidaceae and Malvaceae (2 species each). From these plants, about 11 plant species were studied for their antiviral activity against at least one virus, and 5 plants, namely Adan-sonia digitata, Boscia senegalensis, Hibiscus sabdariffa, Nigella sativa, and Mangifera indica, were tested for their antiviral activity against influenza viruses. The phytoconstituents of the listed plants were summarized, and the antiviral activity of their isolated bioactive compounds was highlighted. Conclusion(s): The review could provide an in-depth theoretical basis and valuable data for designing future studies.Copyright © 2023 Bentham Science Publishers.
ABSTRACT
During the current COVID-19 outbreak, Thai traditional antipyretic recipes and antipyretic herbs have been widely studied. Antipyretic Thai/Lanna herbal decoction for relieving fever in the North consists of Tinospora crispa, Rhinacanthus nasutus, Sauropus androgynus and Alstonia scholaris. This research aimed to study the physical stability, pH, sedimentation, and color of the Lanna antipyretic decoction at 4 degrees C 25 degrees C and 40 degrees C with 75 +or- 5% RH for 7 days. The testing included the Folin Ciocalteu method for quantifying total phenolic content, the aluminium chloride colorimetry for flavonoid content, and the DPPH radical scavenging and ABTS methods for antioxidant activities. The results demonstrated that, for the decoction, the pH values at various temperatures dropped with storage time, the sediment amounts increased with storage time, but its color did not change at 4 degrees C. Its total phenolic and flavonoid contents rose with storage time. The total phenolic contents in mg GAE/g extract at Days 0 and 7 were 161.13 +or- 5.62 and 15.34 +or- 6.21 at 4 degrees C, 160.53 +or- 11.78 and 14.32 +or- 1.13 at 25 degrees C, and 160.09 +or- 7.39 and 12.82 +or- 6.91 at 40 degrees C, respectively;while the flavonoid contents in mgQE/g extract at Days 0 and 7 were 20.32 +or- 0.43 and 7.80 +or- 0.34 at 4 degrees C, 20.10 +or- 0.47 and 7.27 +or- 0.20 at 25 degrees C, and 20.06 +or- 0.55 and 6.63 +or- 0.43 at 40 degrees C, respectively. The decoction's free radical inhibition (IC50) values at 4 degrees C, 25 degrees C and 40 degrees C by DPPH ranged from 14.74 +or- 0.04 to 23.18 +or- 0.72%w/w;and by ABTS the values ranged from 2.63 +or- 0.12 to 3.95 +or- 0.05%w/w. At the storage temperature of 4 degrees C, the decoction showed the best physical stability. Thus, the results can be used in setting up storage guidelines for Thai traditional and folk decoctions to ensue the best stability.
ABSTRACT
As cardiovascular diseases are still a major cause of death in most countries, it is still relevant to look into treatment of such diseases. Dyslipidemia is one of the important identified risk factors for cardiovascular diseases. As this is largely driven by lifestyle and diet, it may be difficult to control it with lifestyle modifications alone. Currently, Statins remains to be the mainstay therapy for dyslipidemia but this is also met by problems within certain patient population. The drug may be contraindicated in certain patient groups;some patients tend to not respond to Statins;while certain patients may not tolerate the adverse events. This study looked into available literature on studies done on dyslipidemia using plant-based formulations using randomized clinical trial. Based on the review conducted, there are several plant-based formations with potential to be similar in efficacy to Statins. Some of the plants used are abundant or may be easily sourced. With the increasing popularity of food supplements or nutraceuticals, exploration on the potential of plant-based products is attractive. Despite the promising results of some studies, these will need further investigations and targeting a larger population size. Formulation options may need to be explored also focused on its stability. © RJPT All right reserved.